Due to her father's illness, which kept him bedridden for eleven years, the family had to move to the house of a paternal uncle, which made it difficult for the future writer to study.
She married medical student Antonio Ángel de Salas in July 1833, had a son in 1841, who died at eleven months, and was widowed in 1843.
In her poem "La poetisa de aldea" (The Village Poetess), a reflection on one from Coronado, she claims the marginal figure of the female poet, alone and isolated in her literary work.
[4] She befriended other poets, such as Amalia Fenollosa [es], Manuela Cambronero, and Rogelia León, and participated in evenings of the Liceo de Badajoz with María Cabezudo and Carolina Coronado.
[7] Her fame grew, and she began to write for various magazines: Periódico científico, literario e industrial, directed by Ramón Ortiz de Zárate [es], that was published four times a month; El Lirio, El despertador montañés, from 1849 to 1853, of which Calixto Fernández Camporredondo was director, and with whom García Miranda began a long epistolary relationship; El Celtíbero de Segorbe (Castellón); Ellas; Órgano oficial del sexo femenino (Madrid), edited by Alicia Pérez de Gascuña, and where her feminist poem "Alzad, hermosas, la abatida frente" appeared.
She expresses why she abandoned poetry in her later years – she initially began writing to alleviate the loneliness due to the deaths of her husband and son.
This was related to the topic of Romanticism: the escape from reality and the search for the exotic, as well as the desire for freedom, which is shown in the poem "A una calandria".