The station was built on the Ferrocarril Panamericano, a line that, since 1908, connected the towns on the coast of Chiapas and Soconusco.

The line also connects the Ferrocarril Transístmico with Guatemala.

[3] Service on the Ixtepec–Ciudad Hidalgo Line, including Villa Comaltitlán, stopped in 2005, due to Hurricane Stan.

[4] However, since 2023, this station is currently being renovated, as part of K Line, a plan to restore passenger rail service from Ixtepec to Ciudad Hidalgo.

[5] As a result, as of October 2023, traders that were previously located near the tracks were preparing to relocate away from the line.