These names are incorrect since they should be exclusively associated with the Villa del Priorato di Malta in Rome.

The villa was later managed by Francesco Orero, and it passed to his sons Gerolamo and Dionisio following his death in 1644.

The latter's financial problems resulted in the property being sold to the Marquis Pier Francesco Cattaneo.

During this period, the building hosted a number of prominent personalities, including Ferdinand I of the Two Sicilies and his brother Giovanni in 1816, and Queen Margherita of Savoy and her brother Thomas of Savoy in the early 20th century.

In a will of 1955, Admiral Franco Spinola made a will leaving the entire property of the villa, including the castle in its grounds, to the Sovereign Military Order of Malta by 1959.