Vincenzo Sicignano (born 8 July 1974 in Pompei, Province of Naples) is an Italian former football goalkeeper turned coach.

After his only Serie A appearance, and two more in the 2003–04 UEFA Cup, Sicignano joined Lecce on loan on 16 January 2004, which became a permanent deal.

He played the 2007-08 season with Frosinone, being transferred from Chievo in a loan (exchange with Massimo Zappino) deal.

He left Frosinone in 2011, after the club suffered relegation from Serie B, to join Barletta in the Lega Pro Prima Divisione league.

[2] After retiring in 2012, Sicignano accepted to return at his former club Palermo as goalkeeping coach of the Under-19 Primavera youth team.