Vinflunine (INN, trade name Javlor) is a novel fluorinated vinca alkaloid derivative[2] undergoing research for the treatment of bladder cancer.

On November 23, 2007, Pierre Fabre Medicament and Bristol-Myers Squibb announced that they were terminating their license agreement for the development of vinflunine, and that Pierre Fabre were continuing "discussions with regulatory authorities and plan to file for the registration of vinflunine for bladder cancer in the first quarter of 2008.

"[4] As of 2012[update], vinflunine was registered for use in Australia for "advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a prior platinum containing regimen," but is not covered under the Pharmaceutical Benefits Scheme.

[5] As of 2016[update], vinflunine was the only commercially-approved agent in some countries for salvage therapy of urothelial carcinoma, (with approval based on the results of a phase III trial), with a reported median OS of about 6 months.

[6][7] It has undergone a phase III clinical trial for advanced transitional cell carcinoma of the urothelial tract.