[5] Virgin River follows Melinda "Mel" Monroe, who answers an ad to work as a midwife and nurse practitioner in the remote Northern California town of Virgin River, thinking it will be the perfect place to start fresh and leave her painful memories behind.

[6] On September 27, 2018, it was announced that Netflix had given the production a series order for a first season consisting of ten episodes.

[5] On December 19, 2018, it was reported that Alexandra Breckenridge, Martin Henderson, Tim Matheson, and Annette O'Toole had been cast in series regular roles.

Additionally, it was further reported that Jenny Cooper, David Cubitt, Lexa Doig, Daniel Gillies, Lauren Hammersley, Benjamin Hollingsworth, Colin Lawrence, Trevor Lerner, and Ian Tracey had joined the cast in an undisclosed capacity.

[9] On October 25, 2021, Mark Ghanimé and Kai Bradbury joined cast as new series regulars for the fourth season.

[11] Principal photography for the series' first season commenced on December 3, 2018, in Vancouver, British Columbia and Saltspring Island, BC and ended on March 26, 2019.

[19] The series was also filmed on location in Snug Cove, Bowen Island,[20] New Westminster, Squamish, Agassiz, and Port Coquitlam, British Columbia.

[26][27] The community of Virgin River is actually Snug Cove, Bowen Island "with establishing shots including the local library, main streets and Artisan Lane", according to one report.

[29] The cabin in the series is the caretaker's house in Murdo Frazer Park, in North Vancouver; this site has been used by other productions as well.

The website's critics consensus reads, "Gentle as a babbling brook—and just as exciting, for better or worse—Virgin River's sophomore season offers up more of the comfort viewing that fans have come to crave.