She received her bachelor's degree in biological science and psychology from Auburn University in August 1968 and taught at Anniston High School prior to a brief unsuccessful marriage.

For professional development, Wetherell attended the John F. Kennedy School of Government at Harvard University in 1997.

The property is near Lamont, an unincorporated community and census-designated place (CDP) 30 miles east of Tallahassee.

Tallahassee's Old Floridan Hotel was the source of four huge 19th-century windows that were placed at the ends of the main hallways on each side of the first floor.

The staircase off the grand foyer used pine from the Old Ormond Hotel which opened in 1888 and was built by Henry Flagler.

Other historic elements from the Ormond Hotel include fireplace mantels, doorknobs, and other hardware.

There are formal living and dining rooms, a library with a comfortable reading area, a parlor with a wet bar, a chef's kitchen outfitted with high-end appliances and an informal dining area; a separate caterer’s kitchen; a butler’s pantry, an office, a Home cinema featuring pediments and light fixtures once in the old Florida Capital building, and a screened porch overlooking the landscaped backyard.

[8][9] John E. Thrasher was chairman of the FSU Board of Trustees when her husband was inducted as President of Florida State University in January, 2003.

Thrasher gave the FSU First Lady a challenge: plan and oversee construction of a new President's residence[10] and secure private funding for the project.

She understood that the project would be a lasting legacy and devoted countless hours researching, planning and monitoring the construction.

[6] After reviewing work done by Historical Concepts Architecture & Planning Company in Atlanta, Mrs. Wetherell chose them and Aaron Dailey as primary architect for the project, and Skip Sheffield, who built the Wetherell's Oak Hill Plantation, was chosen as contractor.

decided he could no longer perform at the level demanded by the president's job, he tendered his resignation and stepped down on January 31, 2010.

Mrs. Wetherell commented, “I’m just flooded with memories today, walking up the steps and seeing how the trees have grown that we transplanted here, seeing the house in such perfect condition.

As of 2023, the Scotts live between Oak Hill Plantation, Lauderdale-By-The-Sea, Florida and Waynesville, North Carolina.