[2] She withdrew from school to help relieve the resulting economic strain on her family, but her father insisted that she finish her education.

[7] An article published in The Crisis years later alleged that the Woman's Medical College of Pennsylvania was hostile toward students of color and that it was extremely difficult to get through the program at all because of the acts of racism that took place there.

[7] With the help of private philanthropy and by working jobs as a clerk, maid, and waitress, Alexander graduated medical school in good standing in 1925.

[3][7] During the 1910s and 20s, aspiring physicians were usually required by law to complete a clinical internship in order to take the state licensing exam and be able to practice medicine.

[7] Aspiranto provided "socialized" health services to African American community members in North Philadelphia.

She would go on to use her position in white Quaker circles to push the cause of improved public health practice for African American patients.

[2] In her community, Alexander was active on the board of Wharton Settlement, the Young Women's Christian Association, the Women's International League for Peace and Freedom, and the Religious Society of Friends, where she was active in the Race Relations Committee, the Institute of Race Relations, and the Young Friends Movement.

[4] Alexander brought social and economic determinants of health to the attention of her white peers, who had not previously considered them to disproportionately impact Black Americans.

[5] During this time period, Alexander received funding from the Rosenwald Foundation, which she used to found the North Philadelphia Clinical Centre.

[7] Eventually, Alexander would go on to teach at the Woman's Medical College of Pennsylvania and work as the Physician-in-Charge of Women Students at Howard University.