[4] In 1930, the college opened its new campus in the East Falls section of Philadelphia, This facility combined teaching and hospital clinical care in one.

Additionally, Mullen worked as a prison agent and established the House of Industry in Philadelphia, a neighborhood center that assisted immigrants and people experiencing homelessness.

Smedley's History of the Underground Railroad cites Bartholomew Fussell as proposing, in 1846, the idea for a college that would train female doctors.

The doctors invited were: Edwin Fussell (Bartholomew's nephew) M.D., Franklin Taylor, M.D., Ellwood Harvey, M.D., Sylvester Birdsall, M.D., and Dr. Ezra Michener.

[5] The Feminist Movement during the early to mid-19th century generated support for the Female Medical College of Pennsylvania.

The Society of Friends in Philadelphia, a large group of Quakers, supported the women's rights movements and the development of the Female MCP.

[19] The Female Medical College of Pennsylvania faced difficulties in providing clinical training for its students,[20] because women oftentimes struggled to be accepted in the male-dominated world of medicine.

When the woman attended lectures in the surgical amphitheater, they were greeted with catcalls and were assaulted with spit, spitballs, and tobacco juice by the male medical students.

[20] In 1887, Anna Broomall, professor of obstetrics for the Woman's Medical College of Pennsylvania, established a maternity outpatient service in a poor area of South Philadelphia for student education.

The first of these was the Ann Preston Building (designed by Thaddeus Longstreth), which provided housing and classrooms for student nurses.

It is operated by Iron Stone Real Estate Partners as student housing, commercial space, and medical offices.

Honoria Acosta-Sison, who graduated in 1909, was the first Filipino woman to become a medical doctor, eventually serving as professor of obstetrics and gynecology and head of the department at the University of the Philippines.

[24] Her thesis addressed “A disquisition on women as physicians.”[25] In 2018, a commemorative historical marker was placed in Mount Vernon, Ohio, where she practiced medicine.

Ann Preston, a member of the first graduating class of the WMCP and later became the first female dean of a medical school in the United States.