[2] During the reign of the emperor Gallienus, Lupus was appointed the senatorial Praeses (governor) of Arabia Petraea (a position he held before 259).
[3] During his term the rhetorician Callinicus of Petra dedicated a work to Lupus, titled On Rhetorical Mannerism.
[4] Following this, during the 260s, Lupus was appointed to the governorship of Syria Coele, which, although nominally subject to Gallienus, placed him under the authority of Odaenathus.
[5] During 271–272, he was serving as governor of Asia, this time his allegiance shifted from Zenobia to the emperor Aurelian.
[6] He was heavily involved in Aurelian's restructure of Zenobian Syria following the emperor's subjugation of the east.