He first appears in Big Bang Comics #1, and was created by Gary Carlson and Mark Lewis.
Vita-Man first appears on the back cover of Big Bang #0 starring in the fictional Red Hot Comics #14.
After numerous reader requests to see Vita-Man in action, he finally gets his own story in Big Bang Comics #27.
With this, he became the superhero Vita-Man (a play on the word vitamin), and later joined the Knights of Justice alongside Ultiman, Venus and Dr. Stellar.
The three Panacea Pills that give Vita-Man his powers empower him with super strength, constitution and speed.