He is a scientific expert on technological innovation at the Ministry for Business and Made in Italy (MIMIT),[1][2] and a member of the Board of Directors of the National Center for Sustainable Mobility Foundation (MOST).

Vito began working formally in the family business in 1980, after graduating as a mechanical industrial expert and teaching at ENAIP.

Upon joining Meridional Meccanica, Pertosa began a process of transforming the business toward the railroad sector, which led to the establishment of MERMEC S.p.A. in 1988.

[13][14] In 2012, he founded SITAEL, an aerospace company with entirely private capital operating in the LEO satellite market and space electric propulsion.

[24] In July 2024, he participated in the G7 Industry Stakeholder Conference in Reggio Calabria, Italy, on the occasion of the G7 Trade Ministers' Meeting.