He came through the youth ranks at hometown club UD Las Palmas, playing for two years with the B team before making the breakthrough in the 2010–11 season, with the Canary Islands side in the Segunda División.

[8] He made his debut in La Liga on 18 August by featuring the full 90 minutes in a 1–3 home loss to Atlético Madrid,[9] and scored his first goal in the competition on 10 November, contributing to a 3–1 away victory over RCD Espanyol.

[20] Deemed surplus to requirements by manager Diego Simeone,[21] Vitolo made only ten appearances in the 2020–21 campaign as the team won their first national championship in seven years.

[25] On 20 March 2015, coach Vicente del Bosque called up former Spain under-19 international Vitolo for the first time to the senior squad for a UEFA Euro 2016 qualifier against Ukraine.

[26] He did not take part in the match, a 1–0 win at his club ground, the Ramón Sánchez Pizjuán Stadium,[27] but made his debut in the following fixture, a 2–0 friendly loss at the Amsterdam Arena to the Netherlands on the 31st, replacing Pedro at half time.