Vitreledonella is a genus of mesopelagic octopods from the family Amphitretidae which contains two species,[1] one of which is the glass octopus.

The eye has strong lateral compression with a near rectangular shape in lateral view and with the width equal to the diameter of the lens.

The opening to the mantle is broad, the radula is multicuspid and linear in form with the first and second lateral tooth each being unicuspid, which means that this species has a heteroglossan radula.

[2] Amphitretus and Bolitaena are two other transparent, gelatinous pelagic incirrate octopods.

Both of these genera differ from Vitreledonella in that the right third arm is hectocotylized and the radula is ctenodont (with comb-like individual teeth).