Vittoria Farnese (29 April 1618 – 10 August 1649) was an Italian noblewoman.

[1] She was born in Parma, the daughter of Ranuccio I Farnese, Duke of Parma and Margherita Aldobrandini, niece of Pope Clement VIII.

On 12 February 1648 she married Francesco I d'Este, widower of her sister Maria Farnese.

[1][2] Vittoria died in Modena in 1649, dying while giving birth to the couple's only child, also called Vittoria (1649–1656).

Francesco then married a third time, to Lucrezia Barberini, in Loreto in October 1654.