[1][2] Epifantsev graduated from the acting faculty of the Boris Shchukin Theatre Institute (1994, course of Vladimir Ivanov), studied at GITIS in the directing Department.

Subsequently, he has twice played in the movies by directed by Svetlana Baskova, Five Bottles of Vodka (2001) and For Marx... (2012).

In 2007, he participated in the TV show King of the Ring under the moniker Stream of Blood (the title of one of his theatrical performances) against Alexey Chumakov.

[4] In 2012, he starred in the TV crime drama, Kremen ("Flint"), in which he acts as Andrey Shamanov, a GRU major who attempts to fight terrorists.

In 2012, along with his wife Anastasiya Vedenskaya, Epifantsev took part in the TV show Polyglot on the channel Culture.