Soon after his graduation in 1988, he founded the new "Ukraine" Symphony Orchestra and as its leader and music director went on tours all over Europe performing and making numerous radio and TV recordings and CD productions.

Volodymyr Sheiko conducted large opera productions and projects in oratorical genres, among them: Yevgeniy Onegin by P. Tchaikovsky; La Traviata and Rigoletto by G. Verdi; Porgy and Bess by G. Gershwin; Carmen by G. Bizet; The Tsar's Bride by N. Rymsky-Korsakov; Il Barbiere di Siviglia by G. Rossini; Cosi fan tutti, Impressario and Le nozze di Figaro by W. A. Mozart; Requiem by G. Verdi; Requiem by M. Reger; Requiem by G. Fauret; Magnificat by J. S. Bach.

Under Volodymyr Sheiko’s direction, the orchestra has presented memorable performances of great musical chedeuvres, among them: "Requiem" by G. Verdi; Symphony No.

2 by S. Rachmaninoff; "Carmina Burana" by Carl Orff; "Stabat Mater" by G. Rossini; "The Execution of Stepan Rasin" by D.Shostakovich; "St. Jonn of Damascus" by S.Taneev; "When the Fern Blooms" by Y. Stankovych; "Requiem" and "Davidde Penitente" by W.A.

During his artistic leadership, Volodymyr Sheiko founded a series of joint musical projects of the Radio Company and National Television Company of Ukraine, such as: “Art Stories”; "RadioSymphony_UA"; “Symphonic Mainstream” and “Message from Ukiraine”, and made more than 500 recordings of world and Ukrainian musical masterpieces for the National Radio Fund.