The votive relief to Isis-Demeter is a Hellenistic marble sculpture discovered in the archaeological site of Dion in Macedonia, Greece.

The dedicatory inscription on the upper left corner of the marble slab reads:[1] Σαράπιδι Ἴσιδι Ἀνούβιδι Καλλίμαχος καὶ Κλήτα χαριστήριον τῆς πλανητέαςAccording to the inscription, a coupled named Callimachus and Cleta offered the relief to the Egyptian divine trinity made up of Isis, Serapis and Anubis as a tribute of their gratitude to the "wandering goddess".

[1][2] It is possible that relief was dedicated to honour profits the couple made thanks to a business deal related to sea voyage.

The relief is considered to be an important source for studying and analysing the cults of the deities of the Egyptian pantheon in regards to trade and seafaring.

[4] Isis' hair then falls freely over the sides of her shoulders, creating spiral locks at various heights.