Sinclair also operates Saginaw-licensed NBC affiliate WEYI-TV (channel 25) under a separate SSA with owner Howard Stirk Holdings.

The three stations share studios on West Pierson Road in Mount Morris Township (with a Flint mailing address); WBSF's transmitter is located at its former studios on West Willard Road in Vienna Township along the Genesee–Saginaw county line (with a Clio mailing address).

[5] With the merger of The WB and UPN to become The CW, WBSF became the area's network affiliate in September 2006 when the channel began broadcasting over the air.

This occurred on Charter's Tri-Cities systems which replaced WKBD with MyNetworkTV affiliate WNEM-DT2 that became the new home of Pistons basketball that year.

In 2006, the channel aired an episode of Friday Night Lights on tape delay due to WEYI's broadcast of the second Michigan gubernatorial debate.

The station may air any preempted NBC program should the preemption occur on WEYI for a local special, breaking news story, any other emergency, or beginning in August 2017, Detroit Lions preseason football.