WDKA (channel 49) is a television station licensed to Paducah, Kentucky, United States, serving as the MyNetworkTV affiliate for Western Kentucky's Purchase region, Southern Illinois and Southeastern Missouri, and Northwest Tennessee.

Both stations share studios on Enterprise Street in Cape Girardeau, while WDKA's transmitter is located in Vienna, Illinois.

In addition to its own digital signal, WDKA is simulcast in standard definition on KBSI's second digital subchannel (23.2) from a transmitter north of Cape Girardeau in unincorporated Cape Girardeau County.

[9] The station's signal is multiplexed: WDKA shut down its analog signal, over UHF channel 49, on February 17, 2009, the original target date on which full-power television stations in the United States were to transition from analog to digital broadcasts under federal mandate (which was pushed back to June 12, 2009).

In October 2019, WDKA reallocated its digital signal onto UHF channel 25 as a result of the station's participation in the FCC's spectrum incentive auction.