It then passes through Albany and then runs concurrently with WIS 104 for 1.2 miles (1.9 km) near Magnolia Bluff Park.

WIS 59 remains concurrent with US 14 until reaching Union then heads east through Cooksville and Edgerton, then junctions with Interstate 39/Interstate 90 (I-90/I-90) and then crossing the Rock River near Newville.

It then heads southeasterly, passing through Milton and then going east and northeast to Whitewater.

It then passes through Palmyra, Eagle, and North Prairie before looping south of Waukesha.

WIS 59 runs parallel to I-94 entering Milwaukee County, routed along National Avenue and Greenfield Avenue, then terminates at WIS 32 south of downtown Milwaukee.