WPFO (channel 23) is a television station licensed to Waterville, Maine, United States, serving the Portland area as an affiliate of the Fox network.

The two stations share studios on Northport Drive in the North Deering section of Portland; WPFO's transmitter is located on Brown Hill west of Raymond.

Paxson sold the station in December 2002 to Corporate Media Consultants Group who changed the call sign to the current WPFO.

The new calls reflected an affiliation change to Fox, which took place on April 7, 2003, filling a gap created in fall 2001 when WPXT (channel 51) switched to The WB.

[7] For a time in the early 2000s, WMPX re-aired some newscasts from WCSH and WLBZ as part of a larger deal between Paxson Communications and Gannett.

[8] In 2003, a three-hour-long weekday morning talk show with a call-in format called So Goes the Nation began airing.

WLOB's program moved to MyNetworkTV affiliate WPME as The Ray Richardson Show and aired from 6:30 to 7:30 until June 2013.

It is aired from a secondary set at WGME's studios on the corner of Washington Avenue and Northport Drive in the North Deering section of Portland.

There is also a live interview desk that was previously used on WGME during news headline updates on that station's weekday morning show and a new light story room which includes a nighttime backdrop of the Portland skyline along with several couches and armchairs.