The second season of the American television series Superman & Lois premiered on The CW on January 11, 2022, and concluded on June 28, 2022, airing 15 episodes.

The series is based on the DC Comics characters Superman and Lois Lane created by Jerry Siegel and Joe Shuster.

The series stars Tyler Hoechlin and Elizabeth Tulloch as the titular characters, Clark Kent / Superman, a costumed superhero, and his wife, Lois Lane who deal with the Inverse Method cult led by Ally Allston who has swayed Lois' sister, Lucy to her side and has made an enemy of Bizarro for her supposed conquering of his world.

Also returning are main cast members Jordan Elsass, Alex Garfin, Erik Valdez, Inde Navarrette, Wolé Parks, Dylan Walsh, and Emmanuelle Chriqui, with Tayler Buck and Sofia Hasmik being promoted from their guest and recurring status in the previous season.

[21] This season features a new design of Superman's suit giving slight adjustment to his boots by adding more red, making it more accurate to the comics.