The hospital has its origins in an infirmary built for the Central Union Workhouse in 1896;[2] the car park is on the site of Walsall Castle, a 12th/13th-15th century moated manor house.

[3] After becoming the Manor Hospital in 1928, it expanded through conversion for clinical use of an old nurses' block in the 1930s and of an old recreational hall in the 1960s.

[2] A redevelopment of the site was procured under a Private Finance Initiative contract in 2007.

The works, which were designed by Steffian Bradley[4] and carried out by Skanska at a cost of £174 million, were completed in 2010.

[7] A new Emergency Department, constructed by Tilbury Douglas was completed in March 2023.