Walter Bowne (26 September 1770 – 31 August 1846) was the 59th Mayor of New York City from 1829 to 1833.

He was a descendant of John Bowne who, with other fellow Quakers was part of the Flushing Remonstrance, one of the earliest establishments of the freedom of religion in North America, and one of the predecessor documents on which the First Amendment to the United States Constitution was based.

Faced with reports of cholera in neighboring towns in 1832, he implemented a strict quarantine policy, regulating travel to and from New York City, and restricting ships to a distance of 300 yd (270 m) from port, and carriages from within 1.5 mi (2.4 km) of the city.

His attempt to prevent an epidemic failed [3]- because it was based on the mistaken but then-accepted notion that transmission of cholera was through personal contact rather than through contaminated water and food, The actual means of transmission was not discovered until 1883.

It is the site where his summer residence stood until a fire destroyed it in March 1925.