Wampusirpi (Spanish pronunciation: [wampuˈsiɾpi]) is a municipality in the Honduran department of Gracias a Dios.

The municipality is located west of the capital city of Puerto Lempira,[1] sharing borders with Ahuas to the north, Gualaco to the west and sharing an international border with Nicaragua to the south.

At the time of the 2013 Honduras census, Wampusirpi municipality had a population of 5,746.

Of these, 86.43% were Indigenous (71.49% Miskito, 14.91% Mayangna), 12.63% Mestizo, 0.42% White, 0.19% Afro-Honduran or Black and 0.32% others.

Terrain roads only exist in the largest locality of Wampusirpi.