The Wapous River is a tributary of the Gouin Reservoir, flowing in the territory of the town of La Tuque, in the administrative region of Mauricie, in Quebec, in Canada.

The Wapous River flows in the townships of Lindsay, Berlinguet, and Déziel, almost at the north-eastern limit of the territory of La Tuque and near the boundary of the administrative region of Saguenay-Lac-Saint-Jean.

The surface of the Wapous River is usually frozen from mid-November to the end of April, however, safe ice circulation is generally from early December to late March.

The Wapous River originates at the mouth of an unidentified lake (length: 0.4 kilometres (0.25 mi) altitude: 526 metres (1,726 ft)).

The toponym "Wapous River" was formalized on December 5, 1968 at the Commission de toponymie du Québec, when it was created.