[4] A Scottish army commanded by Regent Albany besieged Wark in November 1522, and Sir William Lisle defended the castle against the French assault troops, helped by bad weather.

The Earl of Surrey wrote that newly built bulwarks of earth had made the Castle better able to withstand a siege.

[7] In June 1524 Cardinal Wolsey ordered repairs to the keep or donjon walls and lead for the roof was to be brought from Dunstanburgh Castle.

[9] During repairs in September 1542 carts carrying stone from Carham church to the castle were attacked by Scottish raiders.

[10] In 1544, during the war of the Rough Wooing, John Carr, captain of Wark, complained that a length of curtain wall had fallen, near the river.

After peace was concluded in 1559, the Earl of Northumberland asked the Privy Council of England for advice on the future of the castle.

[12] James VI of Scotland passed by on the other side of the Tweed on 26 April 1588 and was saluted by the castle cannon, and he sent a reward of 20 crowns.