[1][3] It is endemic to Mexico and known from the Atlantic slopes of the Sierra Juárez in Oaxaca.

The supratympanic fold is thin but covers the upper edge of the tympanum.

There is mottling that varies from brown, indistinct to more conspicuous gray or almost maroon.

During the daytime, individuals sleeping on leaves have somewhat subdued turquoise-green dorsum.

[2] Quilticohyla acrochorda occurs in mesic cloud forests at elevations of 594–900 m (1,949–2,953 ft) above sea level.