The highway begins at the Port of Windust on the Snake River and travels east to the Lower Monumental Dam and north to SR 260 in Kahlotus, paralleling the Columbia Plateau Trail.

Devils Canyon carried traffic on the Spokane, Portland and Seattle Railway in the early 20th century before the completion of a road serving the Lower Monumental Dam in 1961.

The highway travels east past Windust Park along hills to the northwest and the riverbank on the southeast banks, part of Burr Canyon.

[5] Devils Canyon was originally home to the Portland–Spokane line of the Spokane, Portland and Seattle Railway, completed in 1908 with a small tunnel near the north bank of the Snake River.

[11][12] The rail line fell into disuse by 1987 and the right-of-way was acquired by the Washington State Park System in 1991 to become the Columbia Plateau Trail.