"Watchdogs" originally aired on ABC on March 29, 2016, and according to Nielsen Media Research, was watched by 3.20 million viewers.
The Watchdogs, a militant terrorist organization dedicated to eradicating the Inhumans, destroy an Indiana Advanced Threat Containment Unit (ATCU) facility using nitramene in gel projectiles.
Alphonso "Mack" Mackenzie, who is in the area visiting his brother Ruben, reluctantly leaves and joins Daisy Johnson and Leo Fitz to investigate, and they inform Coulson of the use of nitramene, leading him to suspect the Watchdogs are being led by former S.H.I.E.L.D.
will always use dangerous alien elements to spread terror, and Lincoln reluctantly tries to kill him with Coulson's permission, only to find "Blake" is a hologram.
In March 2016, Marvel announced that the fourteenth episode of the season would be titled "Watchdogs", to be written by Drew Z. Greenberg, with Jesse Bochco directing.
[1] In March 2016, Marvel revealed that main cast members Clark Gregg, Ming-Na Wen, Brett Dalton, Chloe Bennet, Iain De Caestecker, Elizabeth Henstridge, Nick Blood, Adrianne Palicki, Henry Simmons, and Luke Mitchell would star as Phil Coulson, Melinda May, Hive, Daisy Johnson, Leo Fitz, Jemma Simmons, Lance Hunter, Bobbi Morse, Alphonso "Mack" Mackenzie, and Lincoln Campbell, respectively.
The episode connects the series to several other MCU television shows: by featuring the chemical compound nitramene, which was developed by Howard Stark and seen in the Agent Carter episodes "Now is Not the End" and "Bridge and Tunnel";[4] by noting a gang war in Hell's Kitchen, Manhattan, as seen in the second season of Daredevil;[5] and by referencing the company Damage Control, which was the focus of a potential MCU television series of the same name and later seen in Spider-Man: Homecoming.