Waterworks Road transports traffic between the Brisbane central business district and western suburbs such as Red Hill, Ashgrove and The Gap.

Waterworks Road was built on a Turrbal pathway that led to Mount Coot-tha – a place of the honey-bee Dreaming.

The tram line was extended from Red Hill to Jubilee Terrace in 1924, and then to Coopers Camp Road in 1935.

From there it descends rapidly into the Enoggera Creek valley and proceeds west into the gap between the Taylor Range to the north and Mount Coot-tha to the south.

In 2018, it was proposed that Waterworks Road required an upgrade between Trout Street and Beth Eden Terrace in Ashgrove to improve traffic efficiency, reduce congestion and improve safety of road users.