The school was opened in 1999 and resides on the Laboratory campus in Cold Spring Harbor, New York on Long Island.
The school offers a graduate degree (PhD) in molecular biology in an accelerated program that strives for completion within four years.
The school was formerly named after James Watson, co-discoverer of the structure of DNA and then president of the laboratory, shortly after its founding.
On July 1, 2020, the board of trustees voted to return the name of the school to the "Cold Spring Harbor Laboratory School of Biological Sciences" because of Watson's views on race.
[1] The founding dean of the school is Winship Herr, then professor at the University of Lausanne since 2004.