In 1882, Judge James L.A. Webb, a Confederate veteran and a University of North Carolina graduate, operated the only store there and later the Hood Masonic Lodge was built.

In those days most of the groceries and necessities were brought to Hood by flat bottom boat from Sharkey, Mississippi, being hauled down the river from Friars Point.

In July 2001, Earnestine Dixon became the first African American mayor of the town, serving one term (2001–05).

According to the United States Census Bureau, the town has a total area of 0.4 square miles (1.0 km2), all land.

The racial makeup of the town was 35.09% White, 61.33% African American, 2.04% Asian, and 1.53% from two or more races.

The Town of Webb is served by the West Tallahatchie School District.