[1] The species of the genus Weberocereus grows climbing or hanging, epiphytic or lithophytic.

The 2 to 5 ribs have lobed or toothed margins on which are small, sparsely spined areoles.

The bell-shaped to short funnel-shaped flowers that arise on the side of the shoots are mottled pink to yellowish white to green and 3 to 10 centimeters long.

The spherical to oblong, fleshy, often bumpy fruits are red or yellow and bristly or glabrous.

The medium-sized, black-brown to black, slightly shiny seeds are oval and almost smooth.