The Men's 105 kg weightlifting event at the 2007 Pan American Games took place at the Complexo Esportivo Riocentro on 18 July 2007.

[1] All times are Brasilia Time (UTC-3) Prior to this competition, the existing world, Pan American and Games records were as follows: 1 Mafra originally won bronze medal, but was disqualified after he tested positive for abnormal levels of testosterone.

[2]