On 14 February 2010, after helping the under-20 side finish runner-up in the Copa São Paulo de Futebol Júnior,[1] he made his debut with the main squad by starting in a 2–1 Campeonato Paulista home win against Rio Claro.
[2] Ahead of the 2011 season, WWesley Santos as loaned to Campeonato Paulista Série A3 side Sport Barueri.
After featuring sparingly, he returned to Peixe and made his Série A debut on 17 July of that year, starting in a 2–1 home defeat of Atlético Mineiro.
[3] Wesley Santos failed to make any further appearances for the club, being subsequently loaned to Rio Verde[4] and Portuguesa Santista for the 2012 campaign.
[5] Wesley Santos signed for Guarany de Sobral for the 2014 season, but was released on 15 August.