[2] It is one of Australia's two mulga ecoregions, characterized by dry woodlands of mulga trees (Acacia aneura and related species) interspersed with areas of grassland and scrub.

The region consists of the Gascoyne and Murchison bioregions of the Interim Biogeographic Regionalisation for Australia (IBRA).

[5][6] The predominant vegetation is mulga trees, a type of acacia adapted to the hot, dry climate by means of long tap roots.

Wildlife of the region includes red kangaroos and birds such as emus, Australian bustards and honeyeaters.

Most of the area is uninhabited but there is some mining activity and some sheep grazing, both of which cause damage to native habitats.