Wetmoreana appressa is a species of saxicolous (rock-dwelling), crustose lichen in the family Teloschistaceae.

[3] Ulf Arup and colleagues transferred it to the genus Wetmoreana in 2013, as part of a molecular phylogenetics-directed restructuring of the family Teloschistaceae.

[6] The species epithet appressa alludes to the tightly appressed nature of its thallus to the rock substrate.

The type specimen for this species was discovered in Sonora, Mexico, specifically 72 miles east of Hermosillo on the road to Sahuaripa, situated in a thorn forest on rhyolite (a silica-rich volcanic rock) at an elevation of about 1,900 ft (580 m).

[6] A distinctive feature of W. appressa is the presence of calcium oxalate crystals in the medulla of the thallus, visible under polarized light.