White Breast Creek is an important tributary of the Des Moines River in Iowa.

It flows 91.3 miles (146.9 km)[3] from southwest to northeast, rising in Ward Township in Union County, west of Osceola, and flowing in an easterly then a northeasterly direction, to its mouth with the Des Moines River at Lake Red Rock.

Little White Breast Creek enters from the right bank, also in Liberty Township in Lucas County.

A few miles north of Dallas, the creek has a significant floodplain, regularly subject to inundation.

Hawk Run is the last significant tributary, entering near Lake Red Rock on the left bank.