[citation needed] Prince Friedrich was born on 23 August 1891 at Grünholz Castle in Schleswig-Holstein, Kingdom of Prussia.

He was the fifth child and only son of Frederick Ferdinand, Duke of Schleswig-Holstein-Sonderbug-Glücksburg and his wife, Princess Karoline Mathilde of Schleswig-Holstein-Sonderburg-Augustenburg.

[citation needed] Friedrich married his second cousin, Princess Marie Melita of Hohenlohe-Langenburg, daughter of Ernst II, Prince of Hohenlohe-Langenburg and his wife Princess Alexandra of Saxe-Coburg and Gotha, on 5 February 1916 at Coburg.

[citation needed] When the Head of the House of Schleswig-Holstein-Sonderburg-Augustenburg, Albert, Duke of Schleswig-Holstein, died on 27 April 1931, Friedrich's father Friedrich Ferdinand became the Head of the House of Oldenburg and inherited the title of Duke of Schleswig-Holstein.

[citation needed] Duke Friedrich died on 10 February 1965 in Coburg, Bavaria, West Germany.