Wilhelm Olivier Leube

He studied medicine in Tübingen, Zurich, Berlin and Munich, and from 1868 worked as an assistant at the medical clinic in Erlangen.

[1] Wilhelm Leube is remembered for his work with gastric and intestinal disorders that included pioneer research of "nervous dyspepsia".

He believed that gastric irritation was often caused by the effects of food on the sensory nerves of the stomach, and performed extensive studies on digestion.

Later he introduced "test meals" of different types of food, which would be served to patients, and afterwards retrieved via Leube's "gastric tube" at scheduled times.

Through these procedures, Leube researched the degree of digestion of the test meal, as well as the quantity and concentration of acid and pepsin in the patients' stomach.

Leube in 1876