In the north, at Seeburger Straße and the Ziegelhof, the Wilhelmstraße runs into the Klosterstraße, about a kilometre south of Spandau Station.
At its southern end, at the „Seeburger Zipfel“ at Karolinenhöhe the Wilhelmstraße runs into the Potsdamer Chaussee.
In honour of Emperor William I's 100th Birthday in 1897, the Potsdamer Chaussee was renamed north of Karolinenhöhe into „Wilhelmstraße“.
Since the time when Spandau was part of the British Sector of Berlin the „Trainkaserne“ is also known as Smuts Barracks.
It was occupied by seven war criminals, convicted in the Nuremberg Trials, including Rudolf Heß who committed suicide there.