She made numerous voyages between West Africa and the Caribbean in the triangular trade in enslaved people, during which she several times successfully repelled attacks by French privateers.

1st voyage transporting enslaved people (1797–1798): Captain James Locke received a letter of marque for Will on 4 July 1797.

Dolben's Act was the first British legislation passed to regulate slave shipping.

[8] Crow made four voyages to the Bight of Biafra and Gulf of Guinea islands, and then to Jamaica, in 1798, 1800, 1801, and 1802.

2nd voyage transporting enslaved people (1798–1799): Will left Liverpool on 30 July 1798 with a crew of 46 men, bound for Angola.

Near Cape Palmas a French privateer schooner fired on Will, but sheered off on meeting resistance.

Then after Will had been at Bonny for some three months gathering captives, Hugh Crow's brother Will, captain of Charlotte, brought the intelligence that there were three French frigates in the area.

There the nine ships in the harbour organized themselves under the command of Captain Latham of Lottery and sallied forth, anchoring in a line about four miles from the French vessels, which after a week gave up and sailed away.

Crow fought back, driving the privateer off, though not without suffering casualties and a great deal of damage.

Then on 12 April, during a celebration in honour of Rodney's victory, the crew on board a nearby sloop fired a gun that was still loaded with a double-headed shot.

Lloyd's List reported that Diana, of Liverpool, Ward, master, had wrecked on the Bonny Bar, but that the crew was saved, and that Will and Lord Stanley had brought them into Jamaica.

Will encountered Hector, Blackie, master, of Liverpool, which was not part of the convoy but was in a sinking state.

The merchants and underwriters of Liverpool gave him an engraved silver plate worth £200 commemorating him on his feat of driving off three French frigates on 16 December 1799.

The Lloyd's underwriters gave him an engraved silver cup commemorating Crow's defeat of the French privater brig on 21 February 1800.

After collecting captives at Bonny, Crow sailed for the Portuguese island of São Tomé to resupply.

Also, there Crow found the master (Wright), crew, and some captives from the brig John Bull, which had wrecked on the coast of Africa.

Disease broke out among the rescued men and after Crow landed them some time later at Barbados, most died.

[21] Will and Crow arrived back at Liverpool on 23 October 1802,[21] narrowly missing being shipwrecked on the coast of Wales.

[22][d] 6th voyage transporting enslaved people (1804–1805): Captain John Brelsford received a letter of marque on 21 June 1804.

[26] Lloyd's List reported that Will, of and for Liverpool, had been upset by a squall in July 1806 after leaving Kingston and had foundered.