[1] He also appeared in the films The Client (1994), Armageddon (1998), Gone in 60 Seconds (2000), Remember the Titans (2000), The Punisher (2004), American Honey (2016), Halloween (2018), and Minari (2020).

Patton portrayed the evil antagonist in Desperately Seeking Susan (1985) and had a significant role in No Way Out (1987) opposite Kevin Costner,[7] his first major film.

[9] He portrayed coach Bill Yoast in Remember the Titans (2000),[10] and FBI agent Melvin Purvis in the 1991 made-for-television film Dillinger,[11] before a supporting actor performance in Armageddon (1998).

Patton also appeared in Silkwood (1983), The Client (1994), Copycat (1995), The Spitfire Grill (1996), Entrapment (1999), Gone in 60 Seconds (2000),[12] The Mothman Prophecies (2002), The Punisher (2004),[13] The Fourth Kind (2009), Brooklyn's Finest (2010), Minari (2020) and The Forever Purge (2021).

[15] From 2011 to 2015, he starred as Colonel Weaver in the TNT sci-fi television series Falling Skies, executive-produced by Steven Spielberg.

[19] Patton's Yellowstone lead, Kevin Costner, identified Patton in May 2023 as an actor that will join him again, this time in Horizon, a "Civil War saga" based on four scripts which Costner intends to write, direct, and act in, covering a 15-year period of "pre- and post-Civil War... settlement of the American west".