[3] After his junior year, he was selected by the Los Angeles Dodgers in the first round of the 2016 Major League Baseball draft.

[7] He played in seven games for Ogden, 23 for Great Lakes and 25 for the Rancho Cucamonga Quakes of the California League, hitting a combined .246.

[10] He split 2018 between Tulsa and the AAA Oklahoma City Dodgers of the Pacific Coast League, hitting .233 with 20 homers and 59 RBI.

[12] He made his major league debut the following day against the New York Mets and had two hits in four at-bats as the starting catcher.

[14] On June 23, 2019, Smith hit a walk-off three-run home run in the bottom of the ninth inning against the Colorado Rockies.

[15] He returned to the minors for a month and was selected to the Pacific Coast League team at the Triple-A All-Star Game.

[23] In the 2020 World Series against the Tampa Bay Rays, Smith had four hits in 24 at-bats, including a home run in Game 2.

)[20] Smith began 2024 by agreeing to a $8.55 million contract, a record amount for a catcher in his second season of salary arbitration.

[31] On July 5, he hit three home runs in a game against the Milwaukee Brewers, joining Campanella, Piazza, and Yasmani Grandal as the only Dodger catchers to accomplish that.

[34] Smith played in 128 games for the Dodgers in 2024, with a career low .248 batting average and with 20 home runs and 75 RBI.

[20] Smith started every game for the Dodgers in the postseason, but hit poorly, with a .125 average in the NLDS, .182 in the NLCS, and .111 in the 2024 World Series.

[20] On August 29, 2022, Smith announced that he would represent the United States in the 2023 World Baseball Classic, joining fellow Dodgers Mookie Betts and Trea Turner.