William Cayley (May 26, 1807 – February 23, 1890) was a lawyer and political figure in Canada West.
He was born in Saint Petersburg, Russia in 1807, the son of a British consul, and studied in England.
He opened a practice in Toronto, later partnering with Matthew Crooks Cameron.
In 1845, he was chosen as Inspector General, a post in the Executive Council, and elected to the Legislative Assembly in a by-election held in Huron in 1846 and was reelected in 1848.
His son Hugh Cayley became a Member of the Northwest Territories Legislative Assembly serving from 1886 until 1894.