William DuBose (born 1786 or 1787, St. Stephen's Parish (modern Berkeley County, South Carolina); died near Pineville, South Carolina, February 24, 1855) was an American plantation owner, lawyer, and politician who served as lieutenant governor of South Carolina from 1836 to 1838.
The DuBoses were a Huguenot family which had arrived early in the settlement of South Carolina and become prominent.
DuBose was educated at a school in Newport, Rhode Island and then at Yale, graduating in 1807.
[4] He was a presidential elector in 1832, supporting John Floyd of the Nullifier Party,[5] and a member of the South Carolina Nullification Convention in that year.
[7] DuBose was a delegate to the Fourth Convention of Merchants and Others held in Charleston, South Carolina in 1839, part of a series of conventions intended to improve the regional economy.