William Duncan McKay Wylie (1 April 1900 – 21 December 1981) was a farmer, public servant and Canadian federal politician.
Wylie first ran for a seat in the House of Commons of Canada as a Social Credit Party candidate in the 1945 federal election.
He defeated 3 other candidates by a comfortable margin to win the electoral district of Medicine Hat and his 1st term in office.
Wylie would attempt to run for a 3rd term and be re-elected in the 1953 federal election.
He would be nearly defeated by Liberal candidate Harry Veiner.