Sir William Gascoigne (by 1485 – 1540) of Cardington, Bedfordshire was an English Member of Parliament.
[1] He was born the son of George Gascoigne of Cardington.
He was knighted in France at 1520 when attending Henry VIII at the Field of the Cloth of Gold and was also present in 1522 at the state visit of the emperor Charles V. He served Cardinal Wolsey as treasurer of the cardinal's household from 1523 to the cardinal's downfall in 1529 and afterwards served as steward to John Neville, 3rd Baron Latimer.
He represented Bedfordshire in Parliament as a knight of the shire in 1529 and 1536.
He had married twice, with his first marriage being with Elizabeth, the daughter and heiress of John Winter of Cardington, by whom he inherited his Cardington estate and with whom he had his only son and heir, Sir John Gascoigne.